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According to Forrester Research, U.S. online retail sales should exceed $250 billion by 2014, up from $155 billion in 2009. Businesses and entrepreneurs who wish to get a piece of that $250 billion pie need to make sure that when they're setting up their eCommerce website they make good choice on their payment processor. But, with literally hundreds of processors to choose from, which one should you go with? We'll outline the pros and cons of the top three options and explain why you should stick with one of them if you possibly can.